Preclinical Pharmocology

Here are answers to some of the most common questions concerning Cipralex. For more specific questions, we invite you to Ask an Expert here at Lundbeck. Our Medical Advisers are always happy to help.

Is Citalopram easily absorbed and what is its bioavailability?

Citalopram is highly lipophilic and is rapidly absorbed following oral administration. The peak plasma concentration [Cmax] of citalopram...

Is there a receptor antagonist activity related to Citalopram?

In vivo studies in rats have confirmed the absence of receptor antagonist activity in...

What is the degree of protein binding of Citalopram?

Citalopram and its demethylated metabolites bind less extensively to plasma proteins (-80%) than...

How selective is Citalopram?

Citalopram has been shown to be a highly selective inhibitor of serotonin re-uptake both in vitro and...

Can a tolerance to serotonin re-uptake inhibition develop during long-term Citalopram administration?

No tolerance to serotonin re-uptake inhibition develops during long-term citalopram...

Can Citalopram have an effect on ECG?

Citalopram is not cardiotoxic compared with other antidepressants in...

How is Cipramil/Citalopram administered?

Citalopram is available as white, film-coated, scored tablets (round or oval) containing citalopram hydrobromide, corresponding...

Last updated: 10.10.2008
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